Sulfur is like the iodine which is the usual part of each of the cell which is found in the blood of each person. Hence the pure iodine or sulfur alergy is just not possible. Nowadays, there are numerous drugs such as: various antibiotics, anti-inflammatory agents, oral anti-diabetic agents as well as several diuretics which are regularly used having sulfur combination. However, there is much confusion about what comprises the sulfur allergy and its clinical consequences. One question is frequently rose which says whether the patient having sulfur allergy should be administered the medication containing the sulfur and then what other drugs would the patient be alergic to.

Some of the immunological reactions to sulfonamides or sulfur include angioedema, hypotension, immune thrombocytopenia, vasculitis and fixed drug eruptions.